心理科学 ›› 2012, Vol. 35 ›› Issue (2): 477-480.

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精神分裂症患者的记忆损害

林贤浩1,林世泽2,郑金炽3,3,林泽涯3,3,林辉3,3   

  1. 1. 福建医科大学人文学院应用心理学系
    2. 福建医科大学人文学院应用心理系
    3.
  • 收稿日期:2011-03-02 修回日期:2011-10-09 出版日期:2012-03-20 发布日期:2012-03-20
  • 通讯作者: 林贤浩
  • 基金资助:
    福建省自然科学基金项目

The memory impairment in schizophrenia

  • Received:2011-03-02 Revised:2011-10-09 Online:2012-03-20 Published:2012-03-20
  • Contact: Xian HaoLIN

摘要: 摘 要 目的 探讨精神分裂症患者记忆损害状况。方法 采用修正的加工分离记忆实验程序,分别测试精神分裂症患者和正常对照组的记忆能力。结果 (1)精神分裂症患者外显记忆功能存在广泛的缺陷,而内隐记忆功能缺陷只在概念驱动下的测验中出现。(2)以阳性症状为主的精神分裂症患者的外显记忆成绩均高于以阴性症状为主的精神分裂症患者。(3)阴性症状严重程度与外显记忆成绩呈显著负相关。结论 精神分裂症患者的内隐记忆功能相对完整,而外显记忆障碍在以阴性症状为主的精神分裂症患者尤为突出。

关键词: 关键词:精神分裂症, 外显记忆, 内隐记忆

Abstract: Abstract□□Purposes This paper aims at exploring explicit memory and implicit memory impairment in schizophrenia, and making comparisons among patients with different subtypes of schizophrenia in this aspect. Method Fifty-nine patients with schizophrenia and forty normal controls were tested in word perceptual driven experiment, word concept driven experiment, image perceptual driven experiment, image concept driven experiment separately by the method of revised process dissociation procedure,and compared the difference between their explicit memory and implicit memory. At the same time, the patients were divided into two subtypes by the positive and negative symptoms of scale (PANSS), and then compared the change of explicit memory and implicit memory between the two subtypes. In the experiment, there were three sessions, study and test, and an interruption task between study and test. Then calculated the R and A by the method of revised process dissociation procedure, and made comparisons with these data. Results These subjects were tested in the word perceptual driven experiment, word concept driven experiment, image perceptual driven experiment, image concept driven experiment separately, so we could know better explicit memory and implicit memory impairment in patients from different processing mechanism. And it also had a good improvement in accuracy for using the method of revised process dissociation procedure. From this, we learned not only the change of explicit memory, but also implicit memory in schizophrenia, and then we could deepen the further understanding of the cognitive impairment in schizophrenia. the results were as follows: (1)In word concept driven experiment, image perceptual driven experiment, image concept driven experiment, explicit memory results in normal controls were higher than patients, the difference reached statistical significance(P<.01),in word perceptual driven experiment, the results did not differ remarkably(P>0.05).In word concept driven experiment and image concept driven experiment, the implicit memory results in normal controls were higher than patients, the difference reached statistical significance(P<.05),in word perceptual driven experiment and image perceptual driven experiment, the results did not differ remarkably(P>0.05)(2)In the four experimental types, explicit memory results in patients with positive symptoms were higher than those with negative symptoms, the difference reached statistical significance(P<.05;P<.01)but in implicit memory, the results did not differ remarkably(P>0.05).(3)There were no distinct correlations between positive symptoms and explicit memory results in the four experiments. There existed significant inverse correlations between negative symptoms and explicit memory results in the four experiments. There were no distinct correlations between positive, negative symptom and implicit memory in the four experiments. Conclusions The function of implicit memory in schizophrenia was relatively complete, but explicit memory impairment was prominent, especially in patients with negative symptoms. Key words□□Schizophrenia, explicit memory, implicit memory

Key words: Key words:Schizophrenia, explicit memory, implicit memory